Synthetic adsorbents are a series of products based on ion-exchange resin manufacturing
technology, and are designed for the uses as solid extractant. Synthetic adsorbents have
large surface area and fine pore structures inside the particle like activated carbon. For
this porous characteristic, they can effectively adsorb organic compounds from aqueous
solutions. Extraction processes with synthetic adsorbents enables reducing solvent amount
and safer operations compared with conventional solvent extraction techniques.
PROPERTIES
A synthetic adsorbent is spherical particle, and inside it, there exist
effective fine pore structures suitable for the diffusion of solutes
Smaller solutes can penetrate into the
particle by diffusing through the pores, when a solution is allowed to contact with
adsorbent particles.
On the contrary, molecules that are larger than pore size cannot penetrate into the
inside of particle. Consequently, such molecules are not adsorbed on synthetic adsorbents
(this phenomenon is so-called molecular sieving effect).
APPLICATION FIELDS
Synthetic adsorbents are used for the separation of valuable compounds
from plant extracts and fermentation products for pharmaceutical intermediates and food
additives.
STABILITY
Synthetic adsorbents are stable in acidic, alkaline solutions and in
organic solvents, and they can be easily regenerated under mild conditions for repeated
uses.
Types of Synthetic adsorbents and Selection Guide
CHEMICAL STRUCTURE
There are three types of chemical structures for synthetic adsorbents; aromatic,
modified aromatic and methacrylic series.
The chemical structure dominates the degree of hydrophobicity of synthetic adsorbents.
Hydrophobicity of adsorbent is important in selecting a suitable type of adsorbent
according to the chemical nature of target compounds.
Aromatic
Aromatic type adsorbents are
the standard grade and are based on crosslinked polystyrenic matrix. They are widely used
in different industrial fields; extraction of antibiotic intermediates from fermentation
broth, separation of peptides, or food additives, debittering of citrus juice etc.
Modified aromatic type is based on brominated
aromatic matrix which gives enhanced hydrophobicity. This type adsrobent is suitable for
adsorption of organic substances of very low concentration or of highly hydrophilic
substances.
SEPABEADS(R) SP207
Methacrylic
Methacrylic type is based on
methacrylic ester copolymer, and has relatively hydrophilic nature. This type of adsorbent
is suitable for adsorption of polyphenols and surfactants.
DIAION(R) HP2MG
PORE
STRUCTURE
Mitsubishi Chemical supplies wide variety of synthetic adsorbents with
different pore structures. The most appropriate type of adsorbent can be selected
according to the pore size of adsorbent and the molecular size of the target compound (or
sometimes unfavorable compounds to be removed).
Another important parameter is surface area of resins. Adsorbent with
large surface area shows high uptake capacity, especially for small molecules.
PARTICLE SIZE
Standard synthetic adsorbents have ca 0.5 mm mean particle diameter.
This size is designed for most industrial scale processes.
Smaller particle size adsorbents are used for fine
separation/purification applications as reversed-phase chromatographic packing materials.